| Abstract / Summary | 
							Total hip replacement (THR) surgery results in substantial pain relief and functional 
gains. However, deficits in muscle strength and physical function after THR persist. 
Progressive resistance training (PRT) commenced early after THR can potentially 
reduce these deficits and thereby enhance recovery. Traditionally, rehabilitation after 
THR has included movement restrictions to prevent hip dislocations. Improvements 
in surgical techniques and increase of femoral head size may have changed the 
rationale for these restrictions. 
The objectives of this thesis were I) to evaluate the influence of movement restrictions 
and assistive devices on rehabilitation after fast-track THR, II) to assess the inter-rater 
reliability of a test battery of functional performance, muscle strength and leg 
extension power on THR patients and III) to examine whether two weekly sessions of 
supervised PRT in combination with home-based exercise is more effective than 
unsupervised home-based exercise alone in improving leg-extension power of the 
operated leg 10 weeks after THR in patients with perceived functional limitations. 
The thesis consists of three studies (I-III) including patients undergoing primary THR 
due to hip osteoarthritis (OA) at Silkeborg Regional Hospital in the period September 
2010 to November 2012. In Study I, 146 patients treated with movement restrictions 
and a standard package of assistive devices (restricted group) was compared to 219 
patients treated with less movement restrictions and use of assistive devices 
according to individual needs (unrestricted group) in a non-randomised, 
comparative study. Questionnaires on function, pain, quality of life (HOOS), anxiety, 
depression (HADS), working status and patient satisfaction were completed before 
THR, 3 and 6 weeks after. At the 3-week follow-up independency in four different 
activities of daily living (ADL) tasks was evaluated. In Study II, two raters performed 
test and re-test on two samples of 20 patients 3 months after THR. The test battery 
included sit-to-stand performance, 20-metre maximum walking speed, stair climb 
performance, isometric muscle strength (hip abduction/flexion), and leg extension 
power. In Study III, patients were randomly assigned to a control group (n=30) 
performing home-based exercises 7 days/week or an intervention group (n=32) 
performing PRT 2 days/week and home-based exercises the remaining 5 days/week. 
The PRT consisted of four lower extremity exercises performed with loads of 8-12 
repetition maximum (RM) from week 1 to 10 after THR. Outcome was assessed 
before THR and 10 and 26 weeks after by the test battery presented in Study II and 
patient-reported outcome (HOOS). The primary outcome was change in leg 
extension power from baseline to 10-week follow-up. 
Study I showed slightly slower recovery in patient-reported function in the 
unrestricted group compared to the restricted group, but the difference was 
2 
eliminated after 6 weeks and potentially biased by missing answers. The unrestricted 
group was more independent in ADL after 3 weeks and returned earlier to work 
compared to the restricted group, with no differences in the other patient-reported 
outcomes. The reliability study (II) documented acceptable relative and absolute 
inter-rater reliability of the test battery on a group level, but not on an individual 
level. In Study III, the supervised PRT in addition to home-based exercise was not 
superior to home-based exercise alone in improving leg extension power of the 
operated leg after THR. A few secondary outcomes favoured PRT but seemed 
clinically insignificant. 
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